Amplify EyeCare Chattanooga Logo
Authors
Gareth R. Barnes; Xingfeng Li; Benjamin Thompson; Krishna D. Singh; Serge O. Dumoulin; Robert F. Hess

Decreased Gray Matter Concentration in the Lateral Geniculate Nuclei in Human Amblyopes

publication date
2010 Dec 8
Category
see more

Abstract/Introduction

Purpose.: In a group of humans with strabismic amblyopia, the relationship was examined between the structure and function of different brain regions. Three question were addressed: (1) Is the lateral geniculate nucleus (LGN) in humans with amblyopia structurally as well as functionally abnormal? (2) Do structural anomalies in the visual cortex correlate with the previously reported cortical functional losses? (3) Is there a link between the functional anomalies in the visual cortex and any structural anomalies in the geniculate?

Methods.: The structure was compared by using voxel-based morphometry (VBM) and the function by functional magnetic resonance imaging (fMRI).


Conclusion/Results

Results.: The results showed that the geniculate is structurally abnormal in humans with strabismic amblyopia.

Conclusions.: These findings add further weight to the role of the LGN in the cortical deficits exhibited in human strabismic amblyopes.


Contact Us To Amplify Your EyeCare

Working Hours

Monday - Thursday
8:00 am - 5:15pm
friday-sunday
Closed
Location
1043 Executive Drive Suite #101 Hixson, TN 37343
Website Accessibility Policy
Safety protocols page
phone-handsetarrow-uparrow-right linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram